caDmium zINc metAlLOTHioneIN

  • Metallothionein: a Cadmium- and Zinc-containing Protein ...

    SUMDNLRY Metallothionein, a protein of small molecular weight, isolated from equine renal cortex contains 2.9 y. of cadmium, 0.6% of zinc, and 40/, of sulfur. The protein, homogeneous on ultracentrifugation, but containing minor impurities on electrophoresis, does not absorb radiation at and near 280 rnp, corresponding to 3 The Ag+ and p ...

  • Cadmium, zinc, copper and metallothionein levels in

    The concentrations of cadmium, zinc, copper and metallothionein in the autopsy samples of liver among the inhabitants of Łódź (Poland) were determined. The cadmium levels were low in the range of 1.5 to 5.8 μg/g. The concentration of metallothionein determined by the Hg-method was high (0.160–1.665 μmol Hg/g); it was mainly a Zn-thionein. The percentage of hepatic zinc

  • Zinc, cadmium, metallothionein, and progesterone: Do

    1985-7-1 · The increased sensitivity to cadmium during pregnancy could also be related to the effect of progesterone on zinc and cadmium metabolism through the actions of metallothionein (MT). MT is a low molecular weight protein believed to function in cadmium detoxification.

  • Crystal structure of Cd,Zn metallothionein

    The anomalous scattering data from five Cd in the native protein were used to determine the crystal structure of cadmium, zinc (Cd,Zn) metallothionein isoform II from rat liver. The structure of a 4-Cd cluster was solved by direct methods. A 2.3 A resolution electron density map was calculated by it

  • (PDF) Crystals of Cadmium, Zinc Metallothionein

    The interest in metallothionein and its involvement in heavy metal-induced nephropathy is a direct result of studies on the toxic metal, cadmium.

  • Cadmium, zinc and copper in horse kidney metallothionein ...

    1979-12-1 · HORSE KIDNEY METALLOTHIONEIN 345 Amol i kg 32 ~ 59.6 402 29.2 n n I profiles of concentrations of cadmium, zinc, and copper in 5-ml fractions from Sephadex G-75 separation of proteins in the homogenates from three horses; 2A is from a 3-year-old horse with a cadmium concentration in kidney cortex of 0.12 mmole Cd/kg, 2B from a 20-year-old horse ...

  • Cadmium, zinc, copper, and metallothionein levels in the ...

    Bern EM, Kaszper BW, Orlowski C, Piotrowski JK, Wójcik G, Zolnowska E (1993) Cadmium, zinc, copper and metallothionein levels in the kidney and liver of humans from central Poland. Environ Monitor Assess 25:1–13. Google Scholar 8. Bronisz H, Szost T, Lipska M, Zawada M (1983) Cadmium content in cigarettes (in Polish).

  • Cadmium/zinc-metallothionein induces DNA strand breaks

    Kägi JHR, Vallee BL (1961) Metallothionein: a cadmium and zinc-containing protein from equine renal cortex. J Biol Chem 236: 2435–2442. PubMed Google Scholar Kaina B, Lohrer H, Karin M, Herlich P (1990) Overexpressed human metallothionein II A gene protects Chinese hamster ovary cells from killing by alkylating agents.

  • Cadmium, zinc, copper and metallothionein levels in the ...

    Cadmium, zinc, copper and metallothionein levels in the kidney and liver of humans from central Poland. Ewa M. Bem 1, Bronisław W. Kaszper 1, Czesław Orłowski 1, Jerzy K. Piotrowski 1, Gabriela Wójcik 1 & Ewa Żołnowska 1 Environmental Monitoring and Assessment volume 25, pages 1–13 (1993)Cite this article

  • (PDF) Single crystals of cadmium, zinc metallothionein

    Metallothionein is a widely distributed, extremely cysteine-rich, low-molecular-weight protein containing large amounts of cadmium and/or zinc. Metallothionein-1B is

  • Protection by Zinc-Metallothionein (ZnMT) against

    1995-6-1 · Protection by Zinc-Metallothionein (ZnMT) against Cadmium-Metallothionein-Induced Nephrotoxicity 1. CATHERINE DORIAN, CATHERINE DORIAN Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center. Kansas City, Kansas 66160-7417. Search for other works by this author on:

  • Effects of cadmium and zinc on tissue levels of ...

    Although the induced synthesis of metallothionein (MT) after exposure to certain metals has been known for some time, there is little information on the quantitation of MT in various tissues. In this study, tissue MT concentrations were measured by a modified Cd-saturation method in tissues of adult male rats after injection of different metal salts. There were differences in tissue levels of ...

  • Cadmium, zinc, copper and metallothionein levels in the ...

    Cadmium, zinc, copper and metallothionein levels in the kidney and liver of humans from central Poland. Ewa M. Bem 1, Bronisław W. Kaszper 1, Czesław Orłowski 1, Jerzy K. Piotrowski 1, Gabriela Wójcik 1 & Ewa Żołnowska 1 Environmental Monitoring and Assessment volume 25, pages 1–13 (1993)Cite this article

  • Single crystals of cadmium, zinc metallothionein.

    2020-11-6 · THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 258: No, 10, Issue of May 25, pp. 6255-6257,1983 Printedm USA. Single Crystals of Cadmium, Zinc Metallothionein* (Received for publication, December 6, 1982) Karen A. Melis, Daniel C. Carter, and Charles David Stout$ From the Department of Crystallography, University of Pittsburgh, Pittsburgh, Pennsyluania

  • Association of metals (mercury, cadmium and zinc) with ...

    Association of metals (mercury, cadmium and zinc) with metallothionein-like proteins in storage organs of stranded dolphins from the Mediterranean sea (Southern Italy) A. Decataldo, A. D. Leo, S. Giandomenico and N. Cardellicchio, J. Environ. Monit., 2004, 6, 361 DOI: 10.1039/B315685K

  • Regulation of cadmium(2+)/zinc(2+)-stimulated ...

    2019-5-26 · Accumulation of metallothionein and its multiple forms by zinc, cadmium and dexamethasone in human peripheral T and B lymphocytes and monocytes. Chemico-Biological Interactions 1995 , 94 (3) , 225-242.

  • Effect of size on concentrations and cadmium inducibility ...

    2021-11-1 · Concentrations of cadmium, zinc, copper and metallothionein in midgut gland and gills of intermoult (C 4) crabs of different size classes (////), postmoult - C 2 & C 3 - crabs (XXX) [carapace width 56 ± 6 mm] and small, probably C 4 crabs (\\\\) in which the moult stage was determined with less certainty. *: different from intermoult crabs (p ...

  • Dietary zinc reduces uptake but not metallothionein ...

    2010-2-9 · Metallothionein was isolated to determine zinc binding to or induction of this cadmium-binding protein. In animals exposed to cadmium only and to cadmium + zinc, metallothionein was induced. In animals exposed to zinc only, no metallothionein was induced, and zinc did not bind to the metallothionein induced by cadmium.

  • Zinc as a countermeasure for cadmium toxicity | Acta ...

    2020-4-13 · Nephrotoxicity of cadmium-metallothionein: protection by zinc and role of glutathione. Toxicol Appl Pharmacol. 1998;151:276–82. CAS PubMed Google Scholar 116. Fujishiro H, Kubota K, Inoue D ...

  • Effect of metallothionein 1A rs8052394 polymorphism on ...

    2020-8-20 · Effect of metallothionein 1A rs8052394 polymorphism on lead, cadmium, zinc, and aluminum levels in factory workers Preeti Singh, Prasenjit Mitra, Taru Goyal, Pilla VSN Kiran Kumar, Shailja Sharma, and Praveen Sharma

  • Protection by Zinc-Metallothionein (ZnMT) against

    1995-6-1 · Protection by Zinc-Metallothionein (ZnMT) against Cadmium-Metallothionein-Induced Nephrotoxicity 1. CATHERINE DORIAN, CATHERINE DORIAN Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center. Kansas City, Kansas 66160-7417. Search for other works by this author on:

  • Zinc and Cadmium Complexes of a Plant Metallothionein ...

    2009-5-29 · Zinc and Cadmium Complexes of a Plant Metallothionein under Radical Stress: ... The reactions of reductive reactive species, produced by γ irradiation of water, with Zn and Cd complexes of a metallothionein from a plant afford diffusible sulfur-centred radicals generated from methionine residues and sulfide ligands.

  • Single crystals of cadmium, zinc metallothionein.

    2020-11-6 · THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 258: No, 10, Issue of May 25, pp. 6255-6257,1983 Printedm USA. Single Crystals of Cadmium, Zinc Metallothionein* (Received for publication, December 6, 1982) Karen A. Melis, Daniel C. Carter, and Charles David Stout$ From the Department of Crystallography, University of Pittsburgh, Pittsburgh, Pennsyluania

  • Metallothionein Synthesis and Degradation: Relationship

    FIGURE 1. Relationship of cadmium and zinc metallothionein synthesis and degradation to hepatic accumulation of injected cadmium and zinc. nounced influence on the rate of proteolysis. At a substrate to enzyme ratio of 300:1 35S-thionein was more than 80% degraded in about 1.5 hr, whereas about 3 hr was required to degrade zinc metal-

  • Association of metals (mercury, cadmium and zinc) with ...

    Association of metals (mercury, cadmium and zinc) with metallothionein-like proteins in storage organs of stranded dolphins from the Mediterranean sea (Southern Italy) A. Decataldo, A. D. Leo, S. Giandomenico and N. Cardellicchio, J. Environ. Monit., 2004, 6, 361 DOI: 10.1039/B315685K

  • Electrospray ionization mass spectrometry of zinc,

    Rupasri Mandal, Guifeng Jiang, Xing‐Fang Li, Direct evidence for co‐binding of cisplatin and cadmium to a native zinc‐ and cadmium‐containing metallothionein, Applied Organometallic Chemistry, 10.1002/aoc.502, 17, 9, (675-681), (2003).

  • Regulation of cadmium(2+)/zinc(2+)-stimulated ...

    2019-5-26 · Accumulation of metallothionein and its multiple forms by zinc, cadmium and dexamethasone in human peripheral T and B lymphocytes and monocytes. Chemico-Biological Interactions 1995 , 94 (3) , 225-242.

  • The two Caenorhabditis elegans metallothioneins (CeMT‐1 ...

    2010-5-17 · Levels of cadmium (A) and zinc (B) were quantified by ICP-OES in Caenorhabditis elegans wild-type and metallothionein deletion strains cultured in the presence or absence of cadmium (25 μ m) or zinc (340 μ m). Values are the means ± SEM of five replicates.

  • Zinc as a countermeasure for cadmium toxicity | Acta ...

    2020-4-13 · Nephrotoxicity of cadmium-metallothionein: protection by zinc and role of glutathione. Toxicol Appl Pharmacol. 1998;151:276–82. CAS PubMed Google Scholar 116. Fujishiro H, Kubota K, Inoue D ...

  • Specificity of the Metallothionein-1 Response by Cadmium ...

    Occupational and environmental exposure to cadmium is associated with the development of urothelial cancer. The metallothionein (MT) family of genes encodes proteins that sequester metal ions and modulate physiological